Septerna (SEPN)Avoro Capital Advisors LLC added to its stake +100K shares

1.34M

Shares reported · +100K vs prior quarter

0.33%

Disclosed portfolio weight

$25.2M

Reported value

Holdings as of

Sep 30, 2025

Filed

Nov 14, 2025

The story around this disclosure

Every dated public record OQRO holds about the company from 60 days before to 120 days after, oldest first. It shows what was going on; none of it is a stated reason for the trade.

1. Sep 25, 2025Company filing · Form 8-K · Executive change, Reg FDChanged a top executive or board member, and shared information with investors“On September 25, 2025 (the “Appointment Date”), the Board of Directors (the “Board”) of Septerna, Inc. (the “Company”) expanded the size of the Board from seven to eight directors and appointed Keith Gottesdiener, M.D. to serve as a member of the Board and as a Class I director, to hold office for a three-year term expiring at the Company’s annual meeting of stockholders to be held in 2028 and until his successor is…”
2. Nov 10, 2025Company filing · Form 8-K · ResultsReported its results

What came next

1. Mar 9, 2026Company filing · Form 8-K · ResultsReported its results

How to read SEC Form 13F-HR

Form 13F is the quarterly report in which investment managers that oversee $100 million or more list the US-listed stocks and some other securities they held on the last day of the quarter.

Full guide: What is an SEC Form 13F?

What else is on file for Septerna

For Septerna, OQRO holds 1 fund holdings report (13F) dated in the last 90 days.

These are records OQRO holds, counted by their date, not a measure of how much trading took place. Routine paperwork such as option exercises and tax withholding is left out. Everything for the company is on its SEPN page.

How this filing works

• SEC Form 13F

Other disclosures at Septerna

• SEC Form 13F-HRAug 13, 2026
• SEC Form 13F-HRMay 15, 2026
• SEC Form 13F-HRFeb 17, 2026
• SEC Form 13F-HRFeb 17, 2026
• SEC Form 13F-HRFeb 13, 2026
• SEC Form 13F-HRNov 14, 2025

Everything OQRO holds on this company is on its SEPN page.